The article “Prolonged Apnoea after Succinylcholine and Atracurium Administration” by Dr Usama Asad and Dr Nida Shahid examines a case of extended apnoea after using succinylcholine and atracurium, two neuromuscular blocking agents commonly used for surgical induction and intubation. Succinylcholine, a short-acting depolarising agent, and atracurium, a non-depolarising agent, have different elimination processes influenced by various factors.

A 26-year-old male undergoing septorhinoplasty experienced delayed recovery of spontaneous breathing: 25 minutes from succinylcholine and 270 minutes from atracurium. The patient, who was on thioridazine, an antipsychotic that may inhibit the metabolism of these agents, potentially contributing to prolonged paralysis. Additionally, factors like potential hypothermia during surgery could have affected atracurium elimination.

This instance highlights the necessity of conducting thorough preoperative evaluations, including a history of medications and monitoring during the procedure, to avoid problems. Ensuring the operating room is in good condition and a careful dosage of neuromuscular blockers will reduce and manage risks. The authors advise examining the history of medications taken by patients and keeping the temperature at a suitable level inside the operating area to prevent prolonged blockade of neuromuscular nerves throughout surgical procedures. You must ensure optimal conditions in your operating room, and a careful plan for anesthesia management is essential to prevent prolonged recuperation.

READ THE FULL CASE REPORT